Small dose of clonidine mixed with low-dose ropivacaine and fentanyl for epidural analgesia after total knee arthroplasty

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Small dose of clonidine mixed with low-dose ropivacaine and fentanyl for epidural analgesia after total knee arthroplasty.

BACKGROUND We studied whether a small dose of clonidine added to a ropivacaine-fentanyl mixture improves epidural analgesia without provoking side effects typically related to larger amounts of epidural clonidine. METHODS In this randomized, double-blinded study, patients (< or =85 yr, ASA I-III) underwent total knee arthroplasty (TKA) performed under spinal anaesthesia. After the operation, ...

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Intraarticular vs. extraarticular ropivacaine infusion following high-dose local infiltration analgesia after total knee arthroplasty

BACKGROUND AND PURPOSE Ropivacaine infusion following high-volume local infiltration analgesia has been shown to be effective after total knee arthroplasty, but the optimum site of administration of ropivacaine has not been evaluated. We compared the effects of intraarticular and extraarticular adminstration of the local anesthetic for postoperative supplementation of high-volume local infiltra...

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Small-Dose Fentanyl in Intravenous Versus Epidural Preemptive Analgesia

Patients were randomly allocated to one of two groups; intravenous or epidural analgesia, with twenty patients in each group. General anesthesia was induced with thiopentone 5-6 mgkg-1 and maintained with 0.8-1.0% isoflurane and 66% nitrous oxide in 33% O2. The trachea was intubated after administration of vecuronium 0.1 mgkg-1. Patients in the epidural analgesia groups then received, by random...

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A comparison of epidural infusion of 0.2, 0.25, and 0.3% ropivacaine with fentanyl after unilateral total knee arthroplasty

provided the original work is properly cited. CC Epidural patient-controlled analgesia after total knee arthroplasty (TKA), helps patients by decreasing postoperative pain and making early ambulation [1-3]. Ropivacaine is a newly developed amide form of local anesthetics, and is composed of pure S (-) isomers, compared with bupivacaine. Therefore, ropivacaine is free from cardiac toxicity and i...

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Autologous Blood Transfusion after Local Infiltration Analgesia with Ropivacaine in Total Knee and Hip Arthroplasty

Aims. To study the safety of autotransfusion following local infiltration analgesia (LIA) with ropivacaine. Background. Knowledge of blood concentrations of ropivacaine after LIA and autotransfusion is crucial. However, very limited data are available for toxicological risk assessment. Methods. Autotransfusion was studied in patients after total knee arthroplasty (TKA: n = 25) and total hip art...

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ژورنال

عنوان ژورنال: British Journal of Anaesthesia

سال: 2004

ISSN: 0007-0912,1471-6771

DOI: 10.1093/bja/aeh259